Opportunity Information: Apply for PA 18 484
The NIH Research Project Grant (Parent R01, Clinical Trial Not Allowed) is a long-running National Institutes of Health (NIH) funding mechanism designed to support a clearly defined, standalone research project proposed and led by one or more investigators. The central purpose of this opportunity is to fund hypothesis-driven or problem-focused biomedical, behavioral, clinical, or health-related research that fits within the scientific mission and program priorities of at least one participating NIH Institute or Center. In practical terms, applicants are expected to propose a project with a well-scoped set of aims, a strong scientific rationale, and an approach that can be carried out within the proposed budget and project period, with the investigator team bringing the expertise needed to execute the work successfully.
A key restriction in this particular funding announcement is that it does not accept clinical trials. That means applicants must ensure the proposed research does not include prospective assignment of human participants to an intervention (or comparison group) to study the effects of that intervention on health-related outcomes. Projects involving human data or human participants may still be possible depending on the details, but anything that meets NIH's definition of a clinical trial would be considered nonresponsive under this announcement and should instead be routed to an NIH opportunity that explicitly allows clinical trials. This is an important compliance point because a clinical-trial element can make an otherwise strong application ineligible.
The opportunity is issued by NIH as a discretionary grant program and is identified by Funding Opportunity Number PA-18-484, titled "NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)." It is tied to a broad set of CFDA numbers (now commonly referenced through Assistance Listing numbers) spanning many NIH Institutes and Centers, reflecting that it is a "parent" announcement meant to accommodate many scientific areas rather than a single targeted topic. Because it is a parent R01, it generally serves as an entry point for investigator-initiated research ideas, with applicants selecting an NIH Institute or Center assignment aligned with the proposed science.
Eligibility is broad and includes many types of domestic organizations and, notably, certain non-U.S. entities. Eligible applicants listed include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The announcement also highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities (foreign organizations). This wide eligibility is meant to ensure that strong research ideas can come from many sectors and institutional settings, not only traditional academic medical centers.
From the administrative details provided, the opportunity was created on 2017-12-06, with an original closing date shown as 2019-01-07. The listing does not specify an award ceiling or expected number of awards in the provided data, which is common for NIH parent announcements because award size and volume vary by Institute/Center budgets, program priorities, and the scientific merit of submitted applications. In effect, applicants should plan budgets that are appropriate and well-justified for the scope of work and consistent with NIH R01 norms and any Institute-specific guidance, rather than expecting a fixed maximum stated in the announcement summary.
Overall, this opportunity is best understood as NIH's primary pathway for investigator-initiated, non-clinical-trial research projects that are discrete, well-scoped, and aligned with NIH mission areas. Applicants who can articulate a compelling scientific question, propose rigorous methods, and demonstrate the team and environment needed to complete the work, while staying clearly outside the clinical trial definition, are the best fit for this funding announcement.Apply for PA 18 484
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.351, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.859, 93.865, 93.866, 93.867, 93.879.
- This funding opportunity was created on 2017-12-06.
- Applicants must submit their applications by 2019-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 18 484) also looked into and applied for these:
| Funding Opportunity |
|---|
| Academic Research Enhancement Award (Parent R15 Clinical Trial Not Allowed) Apply for PA 18 504 Funding Number: PA 18 504 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $300,000 |
| Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 517 Funding Number: PA 18 517 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 18 574 Funding Number: PA 18 574 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 18 575 Funding Number: PA 18 575 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 586 Funding Number: PA 18 586 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp - Clinical Trial Optional) Apply for PA 18 591 Funding Number: PA 18 591 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 18 589 Funding Number: PA 18 589 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Change of Grantee Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 18 590 Funding Number: PA 18 590 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed ) Apply for PA 18 592 Funding Number: PA 18 592 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 18 648 Funding Number: PA 18 648 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional) Apply for PA 18 658 Funding Number: PA 18 658 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31) Apply for PA 18 666 Funding Number: PA 18 666 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 668 Funding Number: PA 18 668 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 18 671 Funding Number: PA 18 671 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 18 670 Funding Number: PA 18 670 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA)Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 673 Funding Number: PA 18 673 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 18 740 Funding Number: PAR 18 740 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements for Research on Dietary Supplements (Admin. Supp.- Clinical Trial Not Allowed) Apply for PA 18 817 Funding Number: PA 18 817 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $100,000 |
| Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 19 056 Funding Number: PA 19 056 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) Apply for PA 19 116 Funding Number: PA 19 116 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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