Opportunity Information: Apply for PA 16 422
The Large Health Services Research Demonstration and Dissemination Projects for Combating Antibiotic-Resistant Bacteria (CARB) (R18) opportunity (Funding Opportunity Number PA 16-422) is a discretionary grant program run by the Agency for Health Care Research and Quality (AHRQ). It supports large, practical health services research projects that do more than study antibiotic resistance in theory; the emphasis is on real-world demonstration and broad dissemination of approaches that help health care systems prevent, detect, and respond to antibiotic-resistant bacteria. In other words, the program is geared toward applied projects that can be put into practice in health care delivery settings and then shared in a way that helps others replicate or scale what works.
The funding instrument is a grant under the R18 mechanism, which is commonly used for demonstration projects and the spread of proven practices rather than early-stage, exploratory research. Projects funded under this announcement are expected to generate actionable evidence about how to improve care processes, patient safety, and system performance in the context of combating antibiotic-resistant bacteria. AHRQ’s role as a health services research agency is reflected in the focus: strengthening how care is delivered, how decisions are made, how stewardship programs operate, and how interventions are implemented and sustained across different clinical environments.
Eligibility is limited to U.S.-based entities. Foreign institutions cannot apply, and U.S. organizations cannot propose non-U.S. components under this announcement. Eligible applicants, as listed in the source data, include public and state-controlled institutions of higher education, federally recognized Native American tribal governments, and Native American tribal organizations (other than federally recognized tribal governments). Applicants should treat the FOA as the controlling document for full eligibility rules and any additional constraints or requirements that might apply.
The opportunity is associated with CFDA number 93.226 and was created on 2016-09-06. The original closing date shown in the source information is 2021-10-30. The source also notes an expected number of awards of 100, while the award ceiling is not specified in the provided excerpt (it is listed as blank). For practical planning, applicants typically need to consult the full FOA for details on budget limits, allowable costs, project period, review criteria, reporting expectations, and any required attachments or forms.
At a high level, the purpose of this FOA is to move the needle on antibiotic resistance by funding large-scale projects that demonstrate effective strategies in operational health care settings and then actively disseminate the results, tools, workflows, and implementation lessons so that other organizations can adopt them. The emphasis on both demonstration and dissemination signals that successful applications are likely to include not just an intervention, but also a clear plan for implementation, measurement of impact, and a concrete strategy for spreading what is learned to additional sites, stakeholders, or health systems.Apply for PA 16 422
- The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Large Health Services Research Demonstration and Dissemination Projects for Combating Antibiotic-Resistant Bacteria (CARB)(R18)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226.
- This funding opportunity was created on 2016-09-06.
- Applicants must submit their applications by 2021-10-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 100 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments).
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| T Cell Reagent Resource for the Study of Allergic Diseases (U19) Apply for RFA AI 16 027 Funding Number: RFA AI 16 027 Agency: National Institutes of Health Category: Health Funding Amount: $600,000 |
| Technical Assistance for Strengthening of Blood Transfusion Services and Increasing Access to Safe Blood in India under the President’s Emergency Plan for AIDS Relief (PEPFAR) India Apply for CDC RFA GH13 136004CONT17 Funding Number: CDC RFA GH13 136004CONT17 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Support of NIGMS Program Project Grants (P01) Apply for PAR 16 433 Funding Number: PAR 16 433 Agency: National Institutes of Health Category: Health Funding Amount: $6,500,000 |
| NIAID Career Transition Award (K22) Apply for PAR 16 434 Funding Number: PAR 16 434 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76) Apply for RFA AG 17 030 Funding Number: RFA AG 17 030 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| Core Centers for Clinical Research (CCCR) (P30) Apply for RFA AR 17 002 Funding Number: RFA AR 17 002 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Genomics of HIV/AIDS Drug Response and Co-Morbidities (R01) Apply for PA 16 435 Funding Number: PA 16 435 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Building Capacity of the Vietnamese Health System through provision of HIV/AIDS Clinical Care Mentorship and Technical Assistance under the President’s Emergency Plan for AIDS Relief Apply for CDC RFA GH13 136304CONT17 Funding Number: CDC RFA GH13 136304CONT17 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Support of Competitive Research (SCORE) Research Continuance Award (SC3) Apply for PAR 16 437 Funding Number: PAR 16 437 Agency: National Institutes of Health Category: Health Funding Amount: $75,000 |
| Selected Topics in Transfusion Medicine (R21) Apply for PAR 16 441 Funding Number: PAR 16 441 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Selected Topics in Transfusion Medicine (R01) Apply for PAR 16 440 Funding Number: PAR 16 440 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| “South African University-based Technical Assistance Aimed at Improving the quality of HIV/AIDS and related services in the Republic of South Africa under the United States Presidents Emergency Plan for AIDS Relief (PEPFAR)”. Apply for CDC RFA GH15 157403CONT17 Funding Number: CDC RFA GH15 157403CONT17 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| “Support the Strengthening and Utilization of Strategic Information Activities in the Republic of South Africa under the President’s Emergency Plan for AIDS Relief (PEPFAR).” Apply for CDC RFA GH15 157603CONT17 Funding Number: CDC RFA GH15 157603CONT17 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Changes in Cellular Architecture During Aging (R01) Apply for PA 16 442 Funding Number: PA 16 442 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Expanding Alcohol-Focused High-Priority Translational Research for HIV/AIDS (UH2/UH3) Apply for RFA AA 17 015 Funding Number: RFA AA 17 015 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Model Continuums of Care Initiative (MCCI) for Women and Girls at Risk and Living With HIV/AIDS and Harmful Alcohol and Associated Comorbidities Planning Cooperative Agreement (U34) Apply for RFA AA 17 013 Funding Number: RFA AA 17 013 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| Public-Private Partnerships in PEPFAR Countries under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 153903CONT17 Funding Number: CDC RFA GH15 153903CONT17 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Cardiovascular and Pulmonary Research on E-Cigarettes (R01) Apply for RFA HL 17 021 Funding Number: RFA HL 17 021 Agency: National Institutes of Health Category: Health Funding Amount: $300,000 |
| Enhancing Coordination, Integration and Dissemination of Evidence to Combat HIV/AIDS, TB, and Sexually Transmitted Infections (STI) in the Republic of Zambia under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 160203CONT17 Funding Number: CDC RFA GH15 160203CONT17 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
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