Opportunity Information: Apply for PAR 21 230
The Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) is an NIH Fogarty International Center D43 institutional training grant opportunity designed to build long-term research capacity in low- and middle-income countries (LMICs), using the World Bank country income classifications. The core idea is to fund structured research training programs that help LMIC institutions develop a stronger, sustainable pipeline of investigators who can study chronic, non-communicable diseases (NCDs) and related disorders across all stages of life, from early development through older adulthood. The long-range goal is practical and country-relevant: generate the local expertise needed to produce evidence and translate it into interventions, policies, and programs that fit the health realities and resource constraints of the participating countries.
A key feature of this FOA is its flexibility in how partnerships are organized. Applications can be built as collaborations between a U.S. institution and one or more eligible LMIC institutions, which is a common model for training grants that blend U.S.-based mentorship with in-country implementation and research infrastructure development. At the same time, the FOA also allows an LMIC institution to apply without a U.S. partner if the LMIC lead institution can demonstrate a solid track record of externally funded research and/or research training. In either case, the expectation is not short-term workshops or one-off courses, but an institutional program that measurably strengthens local capacity, supports career development, and helps trainees become independent researchers who remain engaged in NCD work in their home settings.
The scientific scope is centered on chronic, non-communicable diseases and disorders across the lifespan, but the application must align primarily with the research interests of at least one of the participating NIH Institutes and Centers (ICs) referenced in the announcement. Applicants can include additional NCD topics, but those are expected to be secondary or complementary rather than the main organizing theme. In practice, this means an application should clearly define its main training emphasis (for example, cardiovascular disease, diabetes, cancer, chronic respiratory disease, mental and neurological disorders, or other major NCD burdens, depending on the NIH IC interests stated in the FOA), explain why that emphasis is a priority in the LMIC context, and show how the training plan, mentorship structure, and research opportunities all support that focus across different life stages.
Another important element is that the FOA is “Clinical Trial Optional,” which affects what trainees can do as part of their research development. The program may support trainees who serve as the lead investigator of an independent clinical trial, conduct an ancillary study linked to an existing trial, or gain meaningful research experience by working on a clinical trial led by another investigator. This gives applicants room to build hands-on trial literacy and trial-related skills into the training program when appropriate, while not requiring that every project be a clinical trial. The emphasis remains on training and career development, with clinical trial involvement treated as a legitimate pathway for building research competencies.
Eligibility is broad and includes many types of organizations, such as public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including both 501(c)(3) and non-501(c)(3) nonprofits). The FOA explicitly recognizes additional applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). Non-U.S. entities (foreign institutions) are eligible to apply, and foreign components are allowed under NIH policy. In addition, non-U.S. components of U.S. organizations may participate, which can matter for U.S. universities that have overseas centers or established field sites.
From an administrative standpoint, this is a discretionary NIH grant in the health funding category, listed under opportunity number PAR-21-230, with CFDA numbers 93.121, 93.213, 93.242, 93.273, 93.313, 93.853, and 93.989. The opportunity was created on May 24, 2021, and the original closing date listed in the provided data is March 11, 2022. The materials provided do not specify an award ceiling or expected number of awards, which typically means applicants need to consult the full FOA text and NIH budget guidance to understand allowable costs, project period expectations, and typical funding levels for the D43 mechanism.
Overall, this FOA is best understood as a capacity-building training grant aimed at creating durable, in-country expertise and institutional strength for NCD research. Competitive applications generally need to show a clear and LMIC-relevant NCD focus aligned with NIH IC priorities, a credible plan for sustained mentorship and skills development, and an institutional strategy that goes beyond training individuals to strengthening the local research environment in a way that continues after the grant ends.Apply for PAR 21 230
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.213, 93.242, 93.273, 93.313, 93.853, 93.989.
- This funding opportunity was created on 2021-05-24.
- Applicants must submit their applications by 2022-03-11. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Frequently Asked Questions (FAQs)
What is the NCD-LIFESPAN Fogarty International Research Training Award (D43)?
The Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) is an NIH Fogarty International Center D43 institutional training grant opportunity. It is designed to build long-term research training capacity in low- and middle-income countries (LMICs) by supporting structured research training programs focused on chronic, non-communicable diseases (NCDs) and related disorders across the lifespan.
What is the primary goal of this funding opportunity?
The long-range goal is to develop durable, in-country expertise and institutional strength so LMIC institutions can generate evidence and translate it into locally relevant interventions, policies, and programs for NCDs, while accounting for real-world resource constraints and health system needs.
What does “across the lifespan” mean in this opportunity?
It means the training program and research emphasis can address NCDs and related disorders at any stage of life, from early development through older adulthood. The intent is to support capacity to study prevention, risk, progression, and outcomes at multiple life stages rather than focusing only on a single age group.
What types of diseases and disorders are within scope?
The scope centers on chronic, non-communicable diseases and disorders. Examples noted include cardiovascular disease, diabetes, cancer, chronic respiratory disease, and mental and neurological disorders, as well as other major NCD burdens, depending on the priorities of the participating NIH Institutes and Centers (ICs) referenced in the announcement.
Does an application have to match specific NIH priorities?
Yes. The application must align primarily with the research interests of at least one of the participating NIH Institutes and Centers (ICs) referenced in the FOA. Additional NCD topics can be included, but they are expected to be secondary or complementary rather than the main organizing theme.
Can an applicant propose multiple NCD topics?
Yes, but the main training emphasis should be clear and should primarily align with at least one participating NIH IC’s interests. Other topics may be included as supporting or complementary elements rather than the central focus.
Is this opportunity focused on short workshops or one-time training events?
No. The expectation is for an institutional program that measurably strengthens local capacity, supports career development, and helps trainees become independent researchers. It is intended to go beyond one-off courses or short-term workshops.
What kinds of partnerships are allowed?
The FOA is flexible. Applications may be submitted as collaborations between a U.S. institution and one or more eligible LMIC institutions. The FOA also allows an LMIC institution to apply without a U.S. partner if the LMIC lead institution can demonstrate a solid track record of externally funded research and/or research training.
Can an LMIC institution apply without a U.S. partner?
Yes. An LMIC institution can apply without a U.S. partner if it can demonstrate a strong track record of externally funded research and/or research training.
How are LMICs defined for this opportunity?
LMIC status is based on the World Bank country income classifications, as referenced in the information provided.
What is the D43 mechanism in practical terms?
In the context provided, D43 refers to an institutional research training grant mechanism intended to build research training capacity at an institutional level, with an emphasis on creating a sustainable pipeline of investigators in LMIC settings.
What is meant by “building long-term research capacity”?
It refers to strengthening the ability of LMIC institutions to train and support investigators over time, including creating a sustainable pipeline of researchers who can continue NCD-focused work in-country and contribute to evidence generation and translation into practice after the grant ends.
What is expected of the training program and mentorship structure?
The program is expected to provide structured, sustained mentorship and skills development, support career development, and offer research opportunities that help trainees become independent researchers who remain engaged in NCD work in their home settings.
Does the FOA support clinical trials?
The FOA is described as “Clinical Trial Optional.” This means clinical trial involvement is permitted but not required, and it can be integrated into training when appropriate.
What does “Clinical Trial Optional” allow trainees to do?
It allows the program to support trainees who (1) serve as the lead investigator of an independent clinical trial, (2) conduct an ancillary study linked to an existing trial, or (3) gain meaningful experience by working on a clinical trial led by another investigator.
Is every trainee project required to be a clinical trial?
No. Clinical trial participation is a legitimate pathway for building research competencies, but the program does not require every project to be a clinical trial. The core emphasis remains research training and career development.
Who is eligible to apply?
Eligibility is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including both 501(c)(3) and non-501(c)(3) nonprofits). Non-U.S. entities (foreign institutions) are eligible to apply, and foreign components are allowed under NIH policy.
Are certain institution types explicitly recognized as eligible?
Yes. The FOA explicitly recognizes additional applicant categories including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and others listed in the opportunity summary provided.
Can a U.S. organization include non-U.S. components (like overseas centers or field sites)?
Yes. The information provided states that non-U.S. components of U.S. organizations may participate, which can include overseas centers or established field sites.
Are foreign components allowed?
Yes. Foreign components are allowed under NIH policy, and non-U.S. entities are eligible to apply based on the information provided.
What is the opportunity number for this FOA?
The opportunity number listed is PAR-21-230.
What agency is offering this grant?
This is an NIH Fogarty International Center funding opportunity, as described in the information provided.
What funding category does this opportunity fall under?
It is listed under the health funding category and described as a discretionary NIH grant.
What are the CFDA numbers associated with this opportunity?
The CFDA numbers provided are 93.121, 93.213, 93.242, 93.273, 93.313, 93.853, and 93.989.
When was this opportunity created?
The opportunity was created on May 24, 2021.
What is the closing date listed in the provided information?
The original closing date listed in the provided data is March 11, 2022.
Does the provided information include an award ceiling or the expected number of awards?
No. The materials provided do not specify an award ceiling or expected number of awards.
Where should applicants look for budget limits, allowable costs, and project period expectations?
The information provided indicates that applicants typically need to consult the full FOA text and NIH budget guidance to understand allowable costs, project period expectations, and typical funding levels for the D43 mechanism.
What makes an application competitive based on the description provided?
Competitive applications generally need to show (1) a clear and LMIC-relevant NCD focus aligned with NIH IC priorities, (2) a credible plan for sustained mentorship and skills development, and (3) an institutional strategy that strengthens the local research environment beyond training individuals, with benefits that can continue after the grant ends.
Is this program intended to help trainees remain engaged in NCD research in their home settings?
Yes. A stated expectation is that the training supports career development and helps trainees become independent researchers who remain engaged in NCD work in their home settings.
Browse more opportunities from the same category: Health
Next opportunity: Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Administrative Resource (U24 Clinical Trials Optional)
Previous opportunity: Department of the Interior – Bureau of Land Management NV Plant Conservation and Restoration Management
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PAR 21 230
Applicants also applied for:
Applicants who have applied for this opportunity (PAR 21 230) also looked into and applied for these:
| Funding Opportunity |
|---|
| Adapting Immunotherapy and Gene Editing Based Strategies for Targeting HIV Reservoirs in the CNS: Potential Benefits and Risks (R01 Clinical Trial Optional) Apply for RFA MH 21 225 Funding Number: RFA MH 21 225 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Adapting Immunotherapy and Gene Editing Based Strategies for Targeting HIV Reservoirs in the CNS: Potential Benefits and Risks (R21 Clinical Trial Optional) Apply for RFA MH 21 226 Funding Number: RFA MH 21 226 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Required) Apply for RFA HL 22 010 Funding Number: RFA HL 22 010 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Not Allowed) Apply for RFA HL 22 011 Funding Number: RFA HL 22 011 Agency: National Institutes of Health Category: Health Funding Amount: $150,000 |
| NIA Postdoctoral Fellowship Award to Promote Diversity in Translational Research for AD/ADRD (F32 Clinical Trial Not Allowed) Apply for PAR 21 217 Funding Number: PAR 21 217 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIA Advanced Postdoctoral Career Transition Awards to Promote Diversity in Translational Research for AD/ADRD (K99/R00 Clinical Trial Not Allowed) Apply for PAR 21 220 Funding Number: PAR 21 220 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIA Predoctoral Fellowship Award to Promote Diversity in Translational Research for AD/ADRD (F31) Apply for PAR 21 218 Funding Number: PAR 21 218 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Diagnostic-Telemedicine Resource (U24 Clinical Trial Not Allowed) Apply for RFA AA 21 012 Funding Number: RFA AA 21 012 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Developmental Project (UH2 Clinical Trial Optional) Apply for RFA AA 21 014 Funding Number: RFA AA 21 014 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Data Coordination Resource (U24 Clinical Trial Not Allowed) Apply for RFA AA 21 013 Funding Number: RFA AA 21 013 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Administrative Resource (U24) (Clinical Trial Not Allowed) Apply for RFA AA 21 011 Funding Number: RFA AA 21 011 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Research Project (U01 Clinical Trial optional) Apply for RFA AA 21 010 Funding Number: RFA AA 21 010 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Non-Human Primate Developmental Genotype-Tissue Expression (NHP dGTEx) Project (U24 Clinical Trials Not Allowed) Apply for RFA HG 21 026 Funding Number: RFA HG 21 026 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIH Directors Transformative Research Awards (R01 Clinical Trial Optional) Apply for RFA RM 21 017 Funding Number: RFA RM 21 017 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Shared Personal Protective Equipment (PPE) Resources (S10 Clinical Trial Not Allowed) Apply for PAR 21 257 Funding Number: PAR 21 257 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Integration, Dissemination, and Evaluation (BRIDGE) Center for the NIH Bridge to Artificial Intelligence (Bridge2AI) Program (U54 Clinical Trial Not Allowed) Apply for RFA RM 21 023 Funding Number: RFA RM 21 023 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Large Research Projects for Prevention of Healthcare-Associated Infections (R01) Apply for PA 21 265 Funding Number: PA 21 265 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $500,000 |
| High Resolution Mapping of Biomolecules in Brain Cells in Aging and Alzheimers Disease (R01 Clinical Trial Not Allowed) Apply for RFA AG 22 019 Funding Number: RFA AG 22 019 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Promoting Bunyavirales Basic Science Research (R01 Clinical Trial Not Allowed) Apply for RFA AI 21 046 Funding Number: RFA AI 21 046 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional) Apply for RFA AG 22 014 Funding Number: RFA AG 22 014 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PAR 21 230", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.